The outstanding properties of magnetic nanoparticles compared to bulk material lie on their small size, they are just a few nanometers in diameter! Such small particles are single domain and at room temperature, they show superparamagnetic behavior: they act as magnets when submitted to a magnetic field of a given magnitude but they act no more as magnets when the external magnetic field comes to zero.
The magnetic properties of the nanoparticles are strongly influenced by their size. A small change of 1nm in the diameter of the NP will change dramatically its properties... That's why having ultramonodisperse NPs is very important. Only by having a very narrow size distribution of nanoparticles, you can unleash all their power.
dasNano, thanks to its proprietary technology, offers you magnetite nanoparticles with different diameters with an accurate control over their particle size and ultra-narrow particle size distribution (down to 5%).
Coated with oleic acid or other surfactants. Stable colloidal dispersions in non-polar solvents (hexane, toluene, etc.) or water.
Magnetic nanoparticles can be used as carriers for drugs when drug molecules are anchored to the surface of the nanoparticles. With the use of an external magnet, the drug can be directed or accumulated in a given body region without surgery or other unpleasant procedures. Then, by applying an alternating magnetic field at precise frequency matched with the NP vibration frequency, temperature is increased and the chemical bond between drug and nanoparticles is broken to release.
Size control means precision: just use the right amount, of the right size, at the right place.
Magnetic nanoparticles can produce heat when submitted to an alternating magnetic field of a given frequency. The optimal frequency to obtain the maximum heating depends, drastically on the particle size. Magnetic nanoparticles can be accumulated close to or inside a tumor and increase the temperature of the surrounding tissues up to 42ºC, just by applying an external alternating magnetic field. At this temperature, healthy cells are not damaged while apoptosis of tumoral cells is induced.
Nanoparticles are high sensitivity sensors due to their diminute size. The magnetic response of magnetic nanoparticles dispersed in a liquid to a magnetic field depends on their hydrodynamic size. In this sense, naked nanoparticles will respond in a different way than nanoparticles anchored to biomolecules, thus allowing the detection of different antibodies or antigens. Therefore, by a tight control of the size, one can control different antibody detection at the same time, and achieve an unprecedented sensitivity. Real time. High sensitivity. Revolution.